Follow these steps to create the Cheddar Bay Biscuit Seafood Pot Pie that will warm your heart and soul:

1. Preheat the Oven: Start by preheating your oven to 375°F (190°C).
2. Prepare Seafood Filling: In a large skillet, melt butter over medium heat. Add shrimp and cook until pink, about 3-4 minutes. Add crab meat and frozen vegetables, stirring gently.
3. Make the Sauce: Sprinkle flour over the seafood mixture. Stir to coat. Gradually pour in the seafood stock and heavy cream, stirring continuously. Bring to a simmer and let it thicken, about 5 minutes.
4. Season the Filling: Add garlic powder, onion powder, dried thyme, salt, and pepper. Mix well and remove from heat.
5. Transfer to Baking Dish: Pour the seafood mixture into a greased 9×13-inch baking dish or a large oven-safe skillet.
6. Prepare Biscuit Topping: In a mixing bowl, combine the Cheddar Bay biscuit mix, shredded cheddar cheese, and milk. Stir until a dough forms.
7. Top the Filling: Spoon dollops of the biscuit dough over the seafood filling, covering it with the mixture.
8. Bake: Place the dish in the preheated oven and bake for 25-30 minutes, or until the biscuit topping is golden brown and cooked through.
9. Cool: Let the dish cool for about 15 minutes before serving to allow the filling to set.
10. Serve: Dish out generous portions and enjoy the comforting blend of seafood and biscuit.